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Tommy Yu
Tommy Yu
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[cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models
Chronological Thread
- From: ak.miller at auckland.ac.nz (Andrew Miller)
- Subject: [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models
- Date: Thu, 31 Jan 2008 12:51:42 +1300
Michael Cooling wrote:
>> if both state variables have the same initial values and
>> rates (which they would...
>>
>
> why should they have the same initial values? I agree if they did then
> it makes
> no difference to the correctness of the model but it seems very possible to
> create a model of system 1 with substance_b and a model of system 2
> with substance_b and give them
> both different initial conditions, then try to combine them. In
> practice I think this would happen more often than not, at least for
> the systems I've dealt with so far.
>
> Are you talking about AFTER you've realised the conflict and have
> already decided which value(s) to go with? Or have I missed something?
>
If two models contradict each other (such as by each stating a initial
value for concentrations of the same species, or a different mechanism
for the exact same reaction), then this contradiction has to be fixed
before the models can be composed.
I am therefore focusing on clean ways to compose non-contradictory
models which involve some overlap of chemical species (and so the
assumption is that the initial values are the same).
Best regards,
Andrew
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Andrew Miller, 01/30/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Michael Cooling, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Andrew Miller, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Michael Cooling, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Andrew Miller, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Michael Cooling, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Andrew Miller, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Michael Cooling, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Michael Cooling, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Andrew Miller, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Michael Cooling, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Andrew Miller, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to createmore re-usable metabolic models, David Nickerson, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to createmore re-usable metabolic models, Andrew Miller, 01/31/2008
- [cellml-discussion] Using proposed CellML 1.2 features to create more re-usable metabolic models, Michael Cooling, 01/31/2008
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