Chronological Thread 

< Chronological >      < Thread >

---

Apologies to Hamid, the message somehow got dropped due to non-membership
status. This was his message.

-------- Original Message --------
Subject: Re: [cellml-discussion] little b - shared models built from reusable
parts
Date: Fri, 25 Jul 2008 12:03:24 -0700
From: Hamid Bolouri <hbolouri at gmail.com>
To: CellML Discussion List <cellml-discussion at cellml.org>
References: <48891484.205 at auckland.ac.nz>
<38142.90.10.100.31.1216988300.squirrel at webmail.ebi.ac.uk>

Maybe I am showing my age, but I think using Lisp for modeling makes a
lot of sense. See

http://www.defmacro.org/ramblings/lisp.html


Hamid
--
http://www.its.caltech.edu/~hbolouri/


On Fri, Jul 25, 2008 at 5:18 AM, Nicolas Le Novere <lenov at ebi.ac.uk> wrote:
> The SBML community has know little b for a while since they first came to
> us, a long time ago, saying roughly "we're much better than you, and we do
> everything in a simpler way, understandable by users".
>
> I think (and this is a personal opinion, that does NOT reflect the opinion
> of the SBML editors as a whole) this is a worthwhile effort, but
> completely different than SBML and CellML.
>
> 1) In general, the terser a language is, the more fuzzy but the harder to
> interpret it is. If the SBML spec is so long and complicated, it is
> because one of our goal is to ensure that everyone interpret an SBML
> description exactly the same way. That bears a lot of consequences on
> units etc. Terse is good. Unambiguous is better (if you want to exchange
> and integrate)
>
> 2) I am not sure LISP is a good *description* language. And we need to
> separate description of the model structure from description of the
> simulation. SBML and CellML are not programming language.
>
> Again this is a personal feeling. At the end I guess the only criteria is
> the usefullness for the scientific community.
>
>> Hi all,
>>
>> Has anyone encountered this before?
>>
>> http://www.littleb.org/
>>
>> The little b project is an effort to provide an open source
>> <http://www.opensource.org/> language which allows scientists to build
>> mathematical models <http://en.wikipedia.org/wiki/Mathematical_model> of
>> complex systems. The initial focus is systems biology
>> <http://en.wikipedia.org/wiki/Systems_biology>. The goal is to stimulate
>> widespread sharing and reuse of models.
>>
>> The little b language is designed to allow biologists to build models
>> quickly and easily from shared parts, and to allow theorists to program
>> new ways of describing complex systems. Currently, libraries have been
>> developed for building ODE
>> <http://en.wikipedia.org/wiki/Differential_equation> models of molecular
>> networks in multi-compartment systems such as cellular epithelia.
>>
>> Little b is based in Common Lisp and contains mechanisms for rule-based
>> reasoning, symbolic mathematics and object-oriented definitions. The
>> syntax is designed to be terse and human-readable to facilitate
>> communication. The environment is both interactive and compilable.
>>
>> Kind regards,
>> James
>>
>> _______________________________________________
>> cellml-discussion mailing list
>> cellml-discussion at cellml.org
>> http://www.cellml.org/mailman/listinfo/cellml-discussion
>>
>
>
> --
> Nicolas LE NOVERE, Computational Neurobiology,
> EMBL-EBI, Wellcome-Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
> Tel: +44(0)1223494521, Fax: +44(0)1223494468, Mob: +44(0)7833147074
> http://www.ebi.ac.uk/~lenov, AIM:nlenovere, MSN:nlenovere at hotmail.com
>
> _______________________________________________
> cellml-discussion mailing list
> cellml-discussion at cellml.org
> http://www.cellml.org/mailman/listinfo/cellml-discussion

---

• [cellml-discussion] [Fwd: Re: little b - shared models built from reusable parts], Tommy Yu, 07/26/2008

---

Archive powered by MHonArc 2.6.18.