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Re: [cellml-discussion] S1S2 Stimulus Protocol in CellML cell model


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  • From: "Cooper, Jonathan" <j.p.cooper AT ucl.ac.uk>
  • To: "cellml-discussion AT cellml.org" <cellml-discussion AT cellml.org>
  • Subject: Re: [cellml-discussion] S1S2 Stimulus Protocol in CellML cell model
  • Date: Thu, 12 Apr 2018 09:47:14 +0000
  • Accept-language: en-GB, en-US
  • Authentication-results: mx1.auckland.ac.nz; dkim=none (message not signed) header.i=none; spf=None smtp.mailfrom=j.p.cooper AT ucl.ac.uk
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Hi Aroli,

I’m not sure I quite understand your question. The plot you link shows both
the AP arising from the last S1 stimulus and the AP from the S2 stimulus. In
the version of S1-S2 restitution there, we do many S1 paces to get the model
to quasi-steady-state. However, it’s possible to write a different version of
the protocol if you want it to do something different. There’s a link to the
protocol<https://travis.cs.ox.ac.uk/FunctionalCuration/protocol/S1S2Restitution/7/v51nc1o/442>
at the top of the results page, so you can see how it’s implemented.

Best wishes,
Jonathan

From:
<cellml-discussion-request AT lists.cellml.org>
on behalf of Aroli Marcellinus
<aroli.marcellinus AT gmail.com>
Reply-To:
"cellml-discussion AT cellml.org"

<cellml-discussion AT cellml.org>
Date: Thursday, 12 April 2018 at 05:05
To:
"cellml-discussion AT cellml.org"

<cellml-discussion AT cellml.org>
Subject: Re: [cellml-discussion] S1S2 Stimulus Protocol in CellML cell model

Hi Cooper,
Thank you for the recommendation. I have looked at the simulator, but can you
explain to me about the simulator? Since I just only found S2 result, but no
S1. How can I simulate both S1 and S2 simulation on
this<https://travis.cs.ox.ac.uk/FunctionalCuration/experiment/tenTusscher2006EpiampS1S2Restitution/21918/201701271721330/23237/outputs_Action_potential_traces_gnuplot_datacsv/663845/displayPlotFlot>
platform?


Aroli Marcellinus
Kumoh Institute of Technology
Computational Medicine Laboratory
61 Daehak-ro (Sinpyeong-dong), Gumi, Gyeongbuk
+82 10 9724 3957
KTalk ID: vondarkness

On Wed, Apr 11, 2018 at 6:41 PM, Cooper, Jonathan
<j.p.cooper AT ucl.ac.uk<mailto:j.p.cooper AT ucl.ac.uk>>
wrote:
Hi Aroli,

You might also want to look at our Web Lab, which has a S1-S2 restitution
protocol - https://chaste.cs.ox.ac.uk/WebLab/db/protocols/7 - run on a range
of models, including post-processing of the raw results. We can give you an
account if you want to add your own CellML files to the collection.

Best wishes,
Jonathan

From:
<cellml-discussion-request AT lists.cellml.org<mailto:cellml-discussion-request AT lists.cellml.org>>
on behalf of Alan Garny
<a.garny AT auckland.ac.nz<mailto:a.garny AT auckland.ac.nz>>
Reply-To:
"cellml-discussion AT cellml.org<mailto:cellml-discussion AT cellml.org>"

<cellml-discussion AT cellml.org<mailto:cellml-discussion AT cellml.org>>
Date: Wednesday, 11 April 2018 at 02:15
To: cellml-discussion Mailing List
<cellml-discussion AT lists.cellml.org<mailto:cellml-discussion AT lists.cellml.org>>
Subject: Re: [cellml-discussion] S1S2 Stimulus Protocol in CellML cell model

Hi Aroli,

Yes, an S1S2 stimulus protocol can be applied to a CellML file. Just replace
the existing stimulus protocol (if any) in the CellML file with your S1S2
stimulus protocol.

Alan

From:
<cellml-discussion-request AT lists.cellml.org<mailto:cellml-discussion-request AT lists.cellml.org>>
on behalf of Aroli Marcellinus
<aroli.marcellinus AT gmail.com<mailto:aroli.marcellinus AT gmail.com>>
Reply-To: cellml-discussion Mailing List
<cellml-discussion AT lists.cellml.org<mailto:cellml-discussion AT lists.cellml.org>>
Date: Wednesday, 11 April 2018 at 1:03 PM
To: cellml-discussion Mailing List
<cellml-discussion AT lists.cellml.org<mailto:cellml-discussion AT lists.cellml.org>>
Subject: [cellml-discussion] S1S2 Stimulus Protocol in CellML cell model

Hello everyone,
I just want to know if the S1S2 stimulus can be applied to CellML cell
models. Is there any reference or method to replace the common stimulus
protocol into S1S2 stimulus protocol?
Thank you



Aroli Marcellinus
Kumoh Institute of Technology
Computational Medicine Laboratory
61 Daehak-ro<https://maps.google.com/?q=61+Daehak-ro&entry=gmail&source=g>
(Sinpyeong-dong), Gumi, Gyeongbuk
+82 10 9724 3957
KTalk ID: vondarkness




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