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[cellml-discussion] embedded stimulus currents in CellML models


Chronological Thread 
  • From: david.nickerson at nus.edu.sg (David Nickerson)
  • Subject: [cellml-discussion] embedded stimulus currents in CellML models
  • Date: Thu, 19 Jul 2007 08:56:20 +0800

> Of course. And in the same sense you could simply delete the stimulus
> protocol component if you didn't want it. I think the issue is in fact a
> curation issue - we are specifying one of our curation 'levels' as
> "model is the same as is described in the paper." If there is a stimulus
> protocol that isn't in the paper in the CellML model, then this curation
> standard is invalidated. This is fine, as it (hopefully) moves the model
> up to the next 'level,' which requires that the model be able to produce
> the appropriate output, but doesn't necessarily require that the model
> be identical to that described in the paper. So the solution is that we
> should really have both.

its also worth pointing out that, at least for electrophysiology models,
most articles will be applying several different stimulus protocols as
well as things like current and voltage clamps. In general, no single
CellML 1.0 model can represent all these - unless you duplicate the
mathematical model several times and have different bound variables in
different parts of the model.




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